Week 7 Discussion 7 NUR 600
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Sally is a 50-year-old female who has been a jogger for several years. She has recently been diagnosed with osteoarthritis. She has been taking Ibuprofen for 3 months but states that it does not help and hurts her stomach. The health care provider prescribes celecoxib (Celebrex) 100 mg orally twice a day.
1. What is the first-line therapy for osteoarthritis and the mechanism of action? (Let this paragraph discuss current evidenced based pharmacological mech of action at cellular level. It must be an academic and scientific not literal.)
2. Sally expresses concern about all the recent news about heart problems and celecoxib (Celebrex). What information should be included in a teaching plan to help her understand about taking celecoxib and the benefits and risks? (Teaching plan must include dosage, drug interactions, contraindications in specific groups of patients, systemic adverse effects, effect of celecoxib on the heart, benefits and risks)
3. Ibuprofen and celecoxib are both nonsteroidal anti-inflammatory drugs. Explain how they are similar and different? (There must be a separate paragraph for similarity and the other for differences)
